Cyanine7.5 NHS ester

Cyanine7.5是一種近紅外熒光染料，具有很長的發射光譜，是此類熒光衍生而來的活性胺產品。

近紅外照射很容易穿透組織因此常應用于體內成像領域。

該產品可以用于標記含有氨基的小分子物質，比如蛋白和多肽，通過近紅外光譜成像技術（NIR imaging）來示蹤他們在有機體內的分布。

中心聚亞甲基基團的增強的穩定性使得量子產率較其母結構Cy7.5® NHS提高20%。

推薦手冊

氨基分子的NHS酯標記

Cy® is a trademark of GE Healthcare.

General properties

Spectral properties

Product citations

• Yang, H.; Mao, H.; Wan, Z.; Zhu, A.; Guo, M.; Li, Y.; Li, X.; Wan, J.; Yang, X.; Shuai, X. et al.Micelles assembled with carbocyanine dyes for theranostic near-infrared fluorescent cancer imaging and photothermal therapy.Biomaterials,2013, 34(36), 9124-9133. doi:10.1016/j.biomaterials.2013.08.022
• Zhou, K.; Liu, H.; Zhang, S.; Huang, X.; Wang, Y.; Huang, G.; Sumer, B.D.; Gao, J.Multicolored pH-Tunable and Activatable Fluorescence Nanoplatform Responsive to Physiologic pH Stimuli.Journal of the American Chemical Society,2012, 134(18), 7803-7811. doi:10.1021/ja300176w

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2. Lin, Y.-A.; Cheetham, A.G.; Zhang, P.; Ou, Y.-C.; Li, Y.; Liu, G.; Hermida Merino, D.; Hamley, I.W.; Cui, H.Multi-Walled Nanotubes Formed by Catanionic Mixtures of Drug Amphiphiles.ACS Nano,2014, 8(12), 12690-12700. doi:10.1021/nn505688b
3. Graen, T.M.D.; Hoefling, M.; Grubmüller, H.AMBER-DYES: Characterization of Charge Fluctuations and Force Field Parameterization of Fluorescent Dyes for Molecular Dynamics Simulations.Journal of Chemical Theory and Computation,2014, 10(12), 5505-5512. doi:10.1021/ct500869p
4. Lu, H.D.; Soranno, D.E.; Rodell, C.B.; Kim, I.L.; Burdick, J.A.Secondary Photocrosslinking of Injectable Shear-Thinning Dock-and-Lock Hydrogels.Advanced Healthcare Materials,2013, 2(7), 1028-1036. doi:10.1002/adhm.201200343

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